Ruminant models of prenatal growth restriction
نویسندگان
چکیده
منابع مشابه
Prenatal programming of insulin secretion in intrauterine growth restriction.
Intrauterine growth restriction (IUGR) impairs insulin secretion in humans and in animal models of IUGR. Several underlying mechanisms have been implicated, including decreased expression of molecular regulators of β-cell mass and function, in some cases shown to be due to epigenetic changes initiated by an adverse fetal environment. Alterations in cell cycle progression contribute to loss of β...
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Survival of children born prematurely or with very low birth weight has increased dramatically in the last decades, but the long term developmental outcome remains a concern. The most common cerebral neuro-pathology observed in case of premature birth is a diffuse white matter abnormality. However, many of the children born prematurely present indeed deficits in their cognitive capacities, in p...
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Foetuses are a source of scientific information to understand the development and evolution of anatomical structures. The bony labyrinth, surrounding the organ of balance and hearing, is a phylogenetically and ecologically informative structure for which still little concerning growth and shape variability is known in many groups of vertebrates. Except in humans, it is poorly known in many othe...
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I . Guinea-pigs were growth-retarded in early life by feeding their mothers a restricted quantity of food during the second half of pregnancy. After birth, all animals were fed ad Iib. Body-weights were recorded weekly and behavioural tests were made on adult males. The animals were then killed and their brains dissected into forebrain, cerebellum and brain stem. These regions were weighed and ...
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Mathematical models can be used to improve performance, reduce cost of production, and reduce nutrient excretion by accounting for more of the variation in predicting requirements and feed utilization in each unique production situation. Mathematical models can be classified into five or more categories based on their nature and behavior. Determining the appropriate level of aggregation of equa...
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ژورنال
عنوان ژورنال: Bioscientifica Proceedings
سال: 2019
ISSN: 2515-0227
DOI: 10.1530/biosciprocs.5.014